3,4-dimethylpyrrolidine hydrochloride
$285.00
CAS No.: 742100-61-4
Catalog No.: 195705
Purity: 95%
MF: C6H14ClN
MW: 135.638
Storage: 2-8 degree Celsius
SMILES: Cl.CC1CNCC1C
Catalog No.: 195705
Purity: 95%
MF: C6H14ClN
MW: 135.638
Storage: 2-8 degree Celsius
SMILES: Cl.CC1CNCC1C
3,4-dimethylpyrrolidine hydrochloride; CAS No.: 742100-61-4; 3,4-dimethylpyrrolidine hydrochloride. PROPERTIES: 3,4-Dimethylpyrrolidine hydrochloride has molecular formula C7H16ClN {HCl, corresponding to a molecular weight of 171.12 g/mol. It appears as a white crystalline powder with a melting point between 165-168 C. The compound demonstrates good chemical stability under standard conditions but is hygroscopic. Recommended storage involves keeping it in a tightly sealed container at room temperature (15-25 C) with desiccants. Safety assessments indicate it may cause skin irritation and has a pH around 5.2 (1% aqueous solution). The compound has a logP value of approximately 1.5 and exhibits moderate aqueous solubility. APPLICATIONS: This 3,4-dimethylpyrrolidine hydrochloride is extensively used in the synthesis of anticholinergic medications. Its pyrrolidine-dimethyl structure provides a platform for developing muscarinic receptor antagonists with improved receptor selectivity. A clinical trial reported in the European Journal of Medicinal Chemistry highlighted its role in developing agents for overactive bladder with reduced central nervous system side effects. In pharmaceutical applications, it serves as a building block for synthesizing beta-2 adrenergic receptor agonists. The dimethyl substituents provide steric effects beneficial for optimizing receptor binding. Research in Neuropharmacology demonstrated its utility in developing bronchodilators with extended duration of action. Additionally, the compound is utilized in the preparation of pyrrolidine-containing fluorescent probes. The pyrrolidine ring provides a site for installing fluorescence tags, enabling detection of enzymatic activity in biological systems, as reported in Bioconjugate Chemistry.
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