(2S,4S)-4-hydroxypyrrolidine-2-carboxamide hydrochloride
$275.00
CAS No.: 851233-67-5
Catalog No.: 193043
Purity: 95%
MF: C5H11ClN2O2
MW: 166.608
Storage: 2-8 degree Celsius
SMILES: Cl.O[C@H]1C[C@H](NC1)C(=O)N
Catalog No.: 193043
Purity: 95%
MF: C5H11ClN2O2
MW: 166.608
Storage: 2-8 degree Celsius
SMILES: Cl.O[C@H]1C[C@H](NC1)C(=O)N
(2S,4S)-4-hydroxypyrrolidine-2-carboxamide hydrochloride; CAS No.: 851233-67-5; (2S,4S)-4-hydroxypyrrolidine-2-carboxamide hydrochloride. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C5H10N2O2 {HCl and a molecular weight of 166.59 g/mol. It demonstrates a melting point in the range of 198-202 C and shows good solubility in water and common polar solvents like methanol. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as (2S,4S)-4-hydroxypyrrolidine-2-carboxamide hydrochloride may cause skin and eye irritation. The hydroxyl group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, (2S,4S)-4-hydroxypyrrolidine-2-carboxamide hydrochloride serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its hydroxyl substituent enables formation of bioactive esters through esterification reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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