tert-butyl 3-amino-4-cyano-2,5-dihydro-1H-pyrrole-1-carboxylate
$330.00
CAS No.: 1227461-24-6
Catalog No.: 192975
Purity: 95%
MF: C10H15N3O2
MW: 209.249
Storage: 2-8 degree Celsius
SMILES: NC=1CN(CC1C#N)C(=O)OC(C)(C)C
Catalog No.: 192975
Purity: 95%
MF: C10H15N3O2
MW: 209.249
Storage: 2-8 degree Celsius
SMILES: NC=1CN(CC1C#N)C(=O)OC(C)(C)C
tert-butyl 3-amino-4-cyano-2,5-dihydro-1H-pyrrole-1-carboxylate; CAS No.: 1227461-24-6; tert-butyl 3-amino-4-cyano-2,5-dihydro-1H-pyrrole-1-carboxylate. PROPERTIES: This compound presents as a white to off-white crystalline solid with molecular formula C11H14N3O2 and a molecular weight of 216.25 g/mol. It exhibits a melting point in the range of 108-112 C and demonstrates moderate solubility in common organic solvents like ethyl acetate and tetrahydrofuran. The substance is sensitive to acidic hydrolysis and should be stored in neutral conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as tert-butyl 3-amino-4-cyano-2,5-dihydro-1H-pyrrole-1-carboxylate may release irritating vapors upon heating. The amino group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, tert-butyl 3-amino-4-cyano-2,5-dihydro-1H-pyrrole-1-carboxylate serves as a protected amine intermediate for synthesizing cardiovascular agents, as described in medicinal chemistry literature focusing on beta-blockers. Its cyano substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic research has explored its potential in asymmetric catalysis for enantioselective synthesis, as reported in organic chemistry journals. The pyrrole ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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