ethyl 2,4-dimethylpyrimidine-5-carboxylate
$200.00
CAS No.: 2226-86-0
Catalog No.: 192965
Purity: 95%
MF: C9H12N2O2
MW: 180.207
Storage: 2-8 degree Celsius
SMILES: CC1=NC=C(C(=N1)C)C(=O)OCC
Catalog No.: 192965
Purity: 95%
MF: C9H12N2O2
MW: 180.207
Storage: 2-8 degree Celsius
SMILES: CC1=NC=C(C(=N1)C)C(=O)OCC
CAS NO.: 2226-86-0; ethyl 2,4-dimethylpyrimidine-5-carboxylate. PROPERTIES: This compound appears as a colorless to pale yellow oil with molecular formula C9H12N2O2 and a molecular weight of 176.20 g/mol. It has a boiling point in the range of 195-200°C at 760 mmHg and demonstrates good solubility in common organic solvents like ethyl acetate and tetrahydrofuran. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25°C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as ethyl 2,4-dimethylpyrimidine-5-carboxylate may release irritating vapors upon heating. The ester group requires careful handling in strongly basic environments. APPLICATIONS: In the pharmaceutical industry, ethyl 2,4-dimethylpyrimidine-5-carboxylate serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrimidine derivatives. Its dimethyl substituents enable improved lipophilicity for enhanced membrane permeability. Additionally, this compound functions as a building block for preparing liquid crystalline materials through formation of mesogenic units. Academic research has explored its utility in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrimidine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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