5-(2-hydroxyethyl)-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
$225.00
CAS No.: 21585-16-0
Catalog No.: 192964
Purity: 95%
MF: C7H10N2O2S
MW: 186.236
Storage: 2-8 degree Celsius
SMILES: OCCC=1C(NC(NC1C)=S)=O
Catalog No.: 192964
Purity: 95%
MF: C7H10N2O2S
MW: 186.236
Storage: 2-8 degree Celsius
SMILES: OCCC=1C(NC(NC1C)=S)=O
5-(2-hydroxyethyl)-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; CAS No.: 21585-16-0; 5-(2-hydroxyethyl)-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one. PROPERTIES: This compound presents as a white to off-white crystalline solid with molecular formula C7H10N2O2S and a molecular weight of 194.23 g/mol. It exhibits a melting point in the range of 142-146 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 5-(2-hydroxyethyl)-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one may cause skin irritation. The hydroxyl group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, 5-(2-hydroxyethyl)-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its hydroxyl substituent enables formation of bioactive esters through esterification reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrimidinone ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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