4-hydroxypyrimidine-5-carboxamide
$300.00
CAS No.: 4786-53-2
Catalog No.: 192970
Purity: 95%
MF: C5H5N3O2
MW: 139.114
Storage: 2-8 degree Celsius
SMILES: OC1=NC=NC=C1C(=O)N
Catalog No.: 192970
Purity: 95%
MF: C5H5N3O2
MW: 139.114
Storage: 2-8 degree Celsius
SMILES: OC1=NC=NC=C1C(=O)N
4-hydroxypyrimidine-5-carboxamide; CAS No.: 4786-53-2; 4-hydroxypyrimidine-5-carboxamide. PROPERTIES: This compound appears as a white crystalline solid with molecular formula C5H5N3O2 and a molecular weight of 147.11 g/mol. It demonstrates a melting point in the range of 188-192 C and shows moderate solubility in polar solvents such as dimethylformamide and dimethyl sulfoxide. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 4-hydroxypyrimidine-5-carboxamide may release irritating vapors upon heating. The hydroxyl and amide groups require careful handling in strongly acidic or basic environments. APPLICATIONS: In medicinal chemistry, 4-hydroxypyrimidine-5-carboxamide serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its hydroxyl substituent enables formation of bioactive esters through esterification reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrimidine ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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