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2,4-diethoxypyrimidine; CAS No.: 20461-60-3; ChemShuttle s 2,4-diethoxypyrimidine serves as a protected nucleobase for oligonucleotide synthesis. The ethoxy groups stabilize the ring against hydrolysis during phosphoramidite coupling, while allowing deprotection under mild acidic conditions. Our services include custom nucleoside synthesis for antisense oligonucleotide development.