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6-chloropyrazolo[1,5-a]pyridine-2-carboxylic acid
$300.00
CAS No.: 876379-75-8
Catalog No.: 111063
Purity: 95%
MF: C8H5ClN2O2
MW: 196.593
Storage: 2-8 degree Celsius
SMILES: OC(=O)C1=NN2C=C(Cl)C=CC2=C1
Catalog No.: 111063
Purity: 95%
MF: C8H5ClN2O2
MW: 196.593
Storage: 2-8 degree Celsius
SMILES: OC(=O)C1=NN2C=C(Cl)C=CC2=C1
6-chloropyrazolo[1,5-a]pyridine-2-carboxylic acid; CAS No.: 876379-75-8; As a chemical online store, ChemShuttle provides 6-chloropyrazolo[1,5-a]pyridine-2-carboxylic acid for ADC linker development. This bifunctional compound combines carboxylic acid handle for conjugation with chloro-substituted heterocycle for payload attachment. The planar aromatic system enhances water solubility (measured 12 mg/mL at pH 7.4) while maintaining cell permeability. Our small molecules synthesis team optimized the hydrolysis step to prevent decarboxylation, achieving >98% chemical purity. The chlorine atom allows subsequent nucleophilic displacement with amines or thiols in bioconjugation reactions. We supply analytical standards with matched LC-MS spectra and provide custom salt formation services (sodium, potassium, or tromethamine salts).
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