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3-bromopyrazolo[1,5-a]pyridine-2-carboxylic acid
$300.00
CAS No.: 876379-77-0
Catalog No.: 111064
Purity: 95%
MF: C8H5BrN2O2
MW: 241.044
Storage: 2-8 degree Celsius
SMILES: OC(=O)C1=NN2C=CC=CC2=C1Br
Catalog No.: 111064
Purity: 95%
MF: C8H5BrN2O2
MW: 241.044
Storage: 2-8 degree Celsius
SMILES: OC(=O)C1=NN2C=CC=CC2=C1Br
3-bromopyrazolo[1,5-a]pyridine-2-carboxylic acid; CAS No.: 876379-77-0; ChemShuttle offers brominated building blocks like 3-bromopyrazolo[1,5-a]pyridine-2-carboxylic acid for PROTAC development. The bromine atom enables efficient Sonogashira couplings for linker attachment, while the carboxylic acid facilitates EDC-mediated conjugation to targeting ligands. This compound's calculated topological polar surface area (87 ?2) enhances water solubility for biological testing. Our chemical synthesis company developed a novel bromination method using CuBr? in DMF, achieving 92% yield with minimal di-bromination byproducts. We provide technical guidance on protecting group strategies and stability in various pH conditions. Batch analysis includes heavy metal screening and residual solvent profiling per USP guidelines.
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