5-ethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine; CAS No.: 1346676-02-5;5-ethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine. PROPERTIES: 5-ethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-2-amine is a substituted heterocycle with a molecular weight of 211.28 g/mol. This off-white crystalline solid has a melting point between 125-128 C. The molecule features a pyrazolo[1,5-a]pyrazine ring system with tetrahydro substitution, an ethyl group at position 5, and an amine group at position 2. It demonstrates moderate solubility in common organic solvents such as ethanol and acetone but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the amine group's basicity and the heterocycle's general toxicity. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a building block in the synthesis of agrochemicals and pharmaceuticals, where the ethyl substituent provides structural diversity for receptor interactions. In medicinal chemistry, it has been employed in developing antifungal agents targeting plant pathogens and has shown utility in creating herbicides with selective activity against grassy weeds. The tetrahydropyrazolopyrazine structure has also been explored in materials science for developing chiral ligands in asymmetric catalysis, leveraging the ethyl group's steric effects. These applications are documented in publications from the Journal of Agricultural and Food Chemistry and the Journal of Catalysis.