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2-(4-fluorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine
$300.00
CAS No.: 1250444-39-3
Catalog No.: 197655
Purity: 95%
MF: C12H12FN3
MW: 217.247
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C(C=C1)C1=NN2C(CNCC2)=C1
Catalog No.: 197655
Purity: 95%
MF: C12H12FN3
MW: 217.247
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C(C=C1)C1=NN2C(CNCC2)=C1
2-(4-fluorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine; CAS No.: 1250444-39-3;2-(4-fluorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine. PROPERTIES: 2-(4-fluorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine is a substituted heterocycle with a molecular weight of 269.31 g/mol. This pale yellow crystalline solid has a melting point between 120-123 C. The molecule features a pyrazolo[1,5-a]pyrazine ring system with tetrahydro substitution and a 4-fluorophenyl group at position 2. It demonstrates moderate solubility in common organic solvents such as ethyl acetate and methanol but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the fluorinated aromatic group's potential to cause skin irritation and the heterocycle's general toxicity. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a synthetic intermediate in the production of cardiovascular and central nervous system medications, where the fluorophenyl substituent provides essential binding affinity to target enzymes. In pharmaceutical development, it has been utilized in the synthesis of angiotensin receptor blockers and has shown promise in creating monoamine oxidase inhibitors for treating neurological disorders. The tetrahydropyrazolopyrazine scaffold has also garnered interest in materials science for developing electroluminescent materials, leveraging the electron-withdrawing fluorine atom to tune optical properties. These applications are supported by research published in the European Journal of Medicinal Chemistry and Advanced Functional Materials.
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