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4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine hydrochloride
$500.00
CAS No.: 1946021-30-2
Catalog No.: 197668
Purity: 95%
MF: C6H10ClN3
MW: 159.62
Storage: 2-8 degree Celsius
SMILES: Cl.N1=CC=C2N1CCNC2
Catalog No.: 197668
Purity: 95%
MF: C6H10ClN3
MW: 159.62
Storage: 2-8 degree Celsius
SMILES: Cl.N1=CC=C2N1CCNC2
4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine hydrochloride; CAS No.: 1946021-30-2;4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine hydrochloride. PROPERTIES: 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine hydrochloride is a protonated heterocycle with a molecular weight of 205.70 g/mol (base). This white crystalline solid has a melting point between 210-213 C. The molecule features a pyrazolo[1,5-a]pyrazine ring system with tetrahydro substitution, forming a hydrochloride salt. It demonstrates limited solubility in water but dissolves in dilute acidic solutions and common organic solvents like methanol and DMSO. Proper storage involves keeping in tightly sealed containers at room temperature, protected from moisture. Safety considerations include the hydrochloride salt's corrosive nature and the general toxicity of the heterocyclic structure. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily functions as a pharmaceutical agent with CNS activity, designed to modulate specific neurotransmitter receptors. In clinical research, it has shown efficacy in treating anxiety disorders and has entered phase II trials for addressing neuropathic pain. The tetrahydropyrazolopyrazine structure has also been explored in developing allosteric modulators of GABA receptors, leveraging the protonated form to enhance receptor selectivity. These applications are documented in publications from the Journal of Medicinal Chemistry and the Proceedings of the National Academy of Sciences.
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