2-(4-bromo-1H-pyrazol-3-yl)pyridine
$200.00
CAS No.: 166196-52-7
Catalog No.: 192869
Purity: 95%
MF: C8H6BrN3
MW: 224.061
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NNC1)C1=NC=CC=C1
Catalog No.: 192869
Purity: 95%
MF: C8H6BrN3
MW: 224.061
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NNC1)C1=NC=CC=C1
2-(4-bromo-1H-pyrazol-3-yl)pyridine; CAS No.: 166196-52-7; 2-(4-bromo-1H-pyrazol-3-yl)pyridine. PROPERTIES: This compound presents as a pale yellow crystalline solid with molecular formula C9H6BrN3 and a molecular weight of 250.07 g/mol. It exhibits a melting point in the range of 102-106 C and demonstrates moderate solubility in common organic solvents like dichloromethane and acetone. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 15 C, protected from light and moisture. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 2-(4-bromo-1H-pyrazol-3-yl)pyridine may release irritating vapors upon heating. The bromo group requires careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, 2-(4-bromo-1H-pyrazol-3-yl)pyridine serves as a key intermediate for synthesizing kinase inhibitors, as described in pharmaceutical research focusing on cancer therapeutics. Its bromo substituent enables participation in cross-coupling reactions for constructing biaryl systems. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyridine ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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