5-cyano-1-methyl-1H-pyrazole-3-carboxylic acid
$450.00
CAS No.: 1519243-10-7
Catalog No.: 192868
Purity: 95%
MF: C6H5N3O2
MW: 151.125
Storage: 2-8 degree Celsius
SMILES: C(#N)C1=CC(=NN1C)C(=O)O
Catalog No.: 192868
Purity: 95%
MF: C6H5N3O2
MW: 151.125
Storage: 2-8 degree Celsius
SMILES: C(#N)C1=CC(=NN1C)C(=O)O
5-cyano-1-methyl-1H-pyrazole-3-carboxylic acid; CAS No.: 1519243-10-7; 5-cyano-1-methyl-1H-pyrazole-3-carboxylic acid. PROPERTIES: This compound appears as a white crystalline solid with molecular formula C7H5N3O2 and a molecular weight of 165.13 g/mol. It demonstrates a melting point in the range of 220-224 C and shows moderate solubility in polar solvents such as dimethylformamide and dimethyl sulfoxide. The substance is sensitive to acidic hydrolysis and should be stored in neutral conditions. Recommended storage conditions include maintaining in tightly sealed containers at temperatures below 20 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 5-cyano-1-methyl-1H-pyrazole-3-carboxylic acid may release toxic fumes upon heating. The cyano group requires careful handling in strongly basic environments. APPLICATIONS: In the pharmaceutical field, 5-cyano-1-methyl-1H-pyrazole-3-carboxylic acid serves as a key intermediate for synthesizing anticancer agents, as documented in medicinal chemistry literature focusing on kinase inhibitors. Its cyano substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its utility in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The carboxylic acid group also facilitates formation of metal coordination complexes, making it valuable for creating luminescent sensors in materials science, as evidenced by inorganic chemistry publications.
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