N2,N2-dimethylpyrazine-2,3-diamine
$400.00
CAS No.: 89488-74-4
Catalog No.: 196341
Purity: 95%
MF: C6H10N4
MW: 138.174
Storage: 2-8 degree Celsius
SMILES: CN(C1=NC=CN=C1N)C
Catalog No.: 196341
Purity: 95%
MF: C6H10N4
MW: 138.174
Storage: 2-8 degree Celsius
SMILES: CN(C1=NC=CN=C1N)C
N2,N2-dimethylpyrazine-2,3-diamine; CAS No.: 89488-74-4; N2,N2-dimethylpyrazine-2,3-diamine. PROPERTIES: This compound features an N2,N2-dimethylpyrazine-2,3-diamine structure, combining dimethylamino substituents on the pyrazine ring. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 148.2 g/mol (C6H10N4). The melting point ranges between 100-105 C, and it exhibits moderate solubility in common organic solvents like ethanol, methanol, and DMSO while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: N2,N2-Dimethylpyrazine-2,3-diamine serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its N2,N2-dimethylpyrazine-2,3-diamine structure allows for participation in various reactions, including nucleophilic substitution at the pyrazine ring and hydrogen bonding interactions through the dimethylamino groups. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The dimethylamino groups provide steric and electronic effects that influence binding interactions with biological targets. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Medicinal Chemistry journals, focusing on the development of novel dimethylaminopyrazine derivatives based on the N2,N2-dimethylpyrazine-2,3-diamine scaffold.
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