3-chloro-5-methylpyrazine-2-carbonitrile
$365.00
CAS No.: 181284-14-0
Catalog No.: 196915
Purity: 95%
MF: C6H4ClN3
MW: 153.572
Storage: 2-8 degree Celsius
SMILES: ClC=1C(=NC=C(N1)C)C#N
Catalog No.: 196915
Purity: 95%
MF: C6H4ClN3
MW: 153.572
Storage: 2-8 degree Celsius
SMILES: ClC=1C(=NC=C(N1)C)C#N
3-chloro-5-methylpyrazine-2-carbonitrile; CAS No.: 181284-14-0; 3-chloro-5-methylpyrazine-2-carbonitrile. PROPERTIES: This chloro-methyl-substituted pyrazine nitrile features molecular formula C?H?ClN? with molecular weight 142.58 g/mol. It generally appears as a white crystalline powder. Soluble in non-polar and slightly polar organic solvents like hexanes and ethyl acetate. Melting point approximately 90-95 C. Exhibits IR absorption for cyano (~2220 cm??) and C-Cl groups (~600-500 cm??). Thermogravimetric analysis reveals weight loss onset above 150 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a chloro-methyl-substituted pyrazine nitrile, 3-chloro-5-methylpyrazine-2-carbonitrile is predominantly utilized in the synthesis of agrochemicals. It serves as a key intermediate in constructing pyrazine-based herbicides, where the chloro and methyl groups provide valuable binding affinity for plant enzymes as demonstrated in pesticide chemistry research (Pest Management Science). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its nitrile functionality enables conjugation to biomolecules via click chemistry reactions (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the pyrazine group contributes to improved flame retardancy and mechanical properties (Polymer International).
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