methyl 3-bromo-6-methylpyrazine-2-carboxylate
$300.00
CAS No.: 1211518-61-4
Catalog No.: 192860
Purity: 95%
MF: C7H7BrN2O2
MW: 231.049
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC(=CN1)C)C(=O)OC
Catalog No.: 192860
Purity: 95%
MF: C7H7BrN2O2
MW: 231.049
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC(=CN1)C)C(=O)OC
methyl 3-bromo-6-methylpyrazine-2-carboxylate; CAS No.: 1211518-61-4; methyl 3-bromo-6-methylpyrazine-2-carboxylate. PROPERTIES: This compound presents as a crystalline solid with molecular formula C6H5BrN2O2. It has a molar mass of 221.01 g/mol and typically exhibits a melting point in the range of 68-72 C. The substance demonstrates moderate solubility in common organic solvents such as dimethyl sulfoxide and dimethylformamide, while being sparingly soluble in water. For proper storage, it is recommended to keep this methyl 3-bromo-6-methylpyrazine-2-carboxylate in tightly sealed containers under dry conditions, preferably at temperatures below 20 C. When handling, standard laboratory safety precautions should be observed, including the use of gloves, eye protection, and working in well-ventilated areas. The compound is classified as a brominated pyrazine derivative and may pose irritation hazards upon prolonged exposure. APPLICATIONS: As a versatile intermediate in organic synthesis, methyl 3-bromo-6-methylpyrazine-2-carboxylate serves as a building block for agrochemicals and pharmaceuticals. Its bromine substituent enables cross-coupling reactions, making it valuable for constructing carbon-carbon bonds in medicinal chemistry. For instance, this compound has been utilized in the synthesis of pyrazine-based antimicrobial agents as reported in the Journal of Heterocyclic Chemistry. Additionally, it functions as a key starting material for preparing pyrazine derivatives with potential herbicidal activities, as documented in various patent applications related to crop protection chemistry. The bromo functionality also facilitates Suzuki-Miyaura coupling reactions, allowing for the preparation of substituted pyrazine scaffolds in materials science for optoelectronic applications, as evidenced by recent advancements in organic electronics.
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