5-hydroxypyrazine-2-carboxamide
$200.00
CAS No.: 13924-96-4
Catalog No.: 192861
Purity: 95%
MF: C5H5N3O2
MW: 139.114
Storage: 2-8 degree Celsius
SMILES: OC=1N=CC(=NC1)C(=O)N
Catalog No.: 192861
Purity: 95%
MF: C5H5N3O2
MW: 139.114
Storage: 2-8 degree Celsius
SMILES: OC=1N=CC(=NC1)C(=O)N
5-hydroxypyrazine-2-carboxamide; CAS No.: 13924-96-4; 5-hydroxypyrazine-2-carboxamide. PROPERTIES: This white to off-white crystalline solid possesses a molecular formula of C5H5N3O2 and a molecular weight of 147.11 g/mol. It demonstrates moderate hygroscopic tendencies and has a melting point between 208-212 C. The compound shows good solubility in polar solvents such as water and ethanol but limited solubility in non-polar organic solvents. Proper storage requires maintaining in airtight containers at room temperature with protection from moisture and light. Safety precautions include avoiding inhalation of dust and using appropriate personal protective equipment due to its potential to cause respiratory irritation. As an oxygen-containing pyrazine derivative, 5-hydroxypyrazine-2-carboxamide requires careful handling in reactive atmospheres. APPLICATIONS: In the pharmaceutical industry, 5-hydroxypyrazine-2-carboxamide serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in pharmaceutical literature focusing on pyrazine derivatives. Its hydroxyl group enables further functionalization for developing analgesic compounds. Additionally, this compound functions as a building block for preparing pyrazine-based dyes and pigments in the chemical industry. Academic research has explored its utility in bioconjugation reactions due to its reactive hydroxyl group, allowing for the creation of fluorescent probes for bioimaging applications, as reported in biochemical journals. The carboxamide group also facilitates coordination with metal ions, making it valuable for preparing coordination polymers and metal-organic frameworks (MOFs) in materials chemistry, as evidenced by studies in crystallography and structural chemistry publications.
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