5-bromo-2,3-dimethylpyrazine
$300.00
CAS No.: 111454-68-3
Catalog No.: WLZ1196
Purity: 95%
MF: C6H7BrN2
MW: 187.04
Storage: 2-8 degree Celsius
SMILES: BrC=1N=C(C(=NC1)C)C
Catalog No.: WLZ1196
Purity: 95%
MF: C6H7BrN2
MW: 187.04
Storage: 2-8 degree Celsius
SMILES: BrC=1N=C(C(=NC1)C)C
CAS NO.: 111454-68-3; 5-bromo-2,3-dimethylpyrazine. PROPERTIES: This halogenated heterocycle combines a bromine substituent with two methyl groups on a pyrazine ring, creating a molecule with characteristic pyrazine odor and chemical reactivity. The 5-bromo-2,3-dimethylpyrazine typically presents as a colorless to pale yellow liquid with low aqueous solubility but good solubility in organic solvents like dichloromethane and ethyl acetate. Its molecular structure includes an electrophilic bromine atom that renders the molecule reactive toward nucleophilic substitution reactions. For optimal stability and to prevent degradation, this compound should be stored at 2-8 degree Celsius in an amber glass bottle under an inert atmosphere. When handling, appropriate safety measures including nitrile gloves, safety goggles, and proper ventilation are essential. This compound is sensitive to light and moisture, requiring careful environmental control during storage and use. In case of skin contact, wash immediately with soap and water; if eye contact occurs, rinse thoroughly and seek medical evaluation. APPLICATIONS: The 5-bromo-2,3-dimethylpyrazine serves as a versatile building block in agrochemical and pharmaceutical research, particularly for synthesizing pyrazine-containing bioactive molecules. The bromine substituent provides a handle for cross-coupling reactions, enabling the creation of substituted pyrazine derivatives with diverse biological activities. In medicinal chemistry, this compound functions as an intermediate for developing herbicides, fungicides, and antimicrobial agents where the pyrazine scaffold contributes to target binding and efficacy. Additionally, the molecule finds utility in flavor and fragrance industries where its characteristic pyrazine odor can be harnessed for creating specific sensory profiles. Researchers utilizing this compound can leverage its reactive bromine atom to advance syntheses of complex heterocyclic systems for various applications in chemical biology and materials science.
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