5,6-dichloropyrazine-2-carboxylic acid
$600.00
CAS No.: 76537-42-3
Catalog No.: 197276
Purity: 95%
MF: C5H2Cl2N2O2
MW: 192.989
Storage: 2-8 degree Celsius
SMILES: ClC=1N=CC(=NC1Cl)C(=O)O
Catalog No.: 197276
Purity: 95%
MF: C5H2Cl2N2O2
MW: 192.989
Storage: 2-8 degree Celsius
SMILES: ClC=1N=CC(=NC1Cl)C(=O)O
5,6-dichloropyrazine-2-carboxylic acid; CAS No.: 76537-42-3; 5,6-dichloropyrazine-2-carboxylic acid. PROPERTIES: This dichloro-substituted pyrazine carboxylic acid features molecular formula C?H?Cl?N?O? with molecular weight 191.00 g/mol. It typically exists as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 150-155 C. Exhibits IR absorption for carboxylic acid (~2900-2500 cm??) and C-Cl groups (~600-500 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: As a dichloro-substituted pyrazine carboxylic acid, 5,6-dichloropyrazine-2-carboxylic acid is predominantly utilized in the synthesis of antiviral agents. It serves as a key intermediate in constructing pyrazine-based nucleoside analogs, where the dichloro substituents provide enhanced binding affinity for viral polymerases as demonstrated in medicinal chemistry research (Antiviral Research). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its carboxylic acid functionality enables conjugation to biomolecules via amide bond formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the pyrazine ring contributes to improved flame retardancy and mechanical properties (Polymer International).
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