3,5-dibromo-N,N-dimethylpyrazin-2-amine
$300.00
CAS No.: 84539-07-1
Catalog No.: 196330
Purity: 95%
MF: C6H7Br2N3
MW: 280.951
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC=C(N1)Br)N(C)C
Catalog No.: 196330
Purity: 95%
MF: C6H7Br2N3
MW: 280.951
Storage: 2-8 degree Celsius
SMILES: BrC=1C(=NC=C(N1)Br)N(C)C
3,5-dibromo-N,N-dimethylpyrazin-2-amine; CAS No.: 84539-07-1; 3,5-dibromo-N,N-dimethylpyrazin-2-amine. PROPERTIES: This compound features a 3,5-dibromo-N,N-dimethylpyrazin-2-amine structure, combining two bromine atoms, dimethylamino substituents, and a pyrazine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 267.0 g/mol (C4H5Br2N3). The melting point ranges between 150-155 C, and it exhibits moderate solubility in common organic solvents like DMSO and DMF while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 3,5-Dibromo-N,N-dimethylpyrazin-2-amine serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 3,5-dibromo-N,N-dimethylpyrazin-2-amine structure allows for participation in various reactions, including palladium-catalyzed cross-coupling reactions at the bromine positions and nucleophilic substitution at the pyrazine ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The bromine atoms provide handles for introducing aryl, vinyl, or heterocyclic substituents. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel dibromopyrazine derivatives based on the 3,5-dibromo-N,N-dimethylpyrazin-2-amine scaffold.
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