(S)-N-(tetrahydro-2H-pyran-3-yl)benzamide
$300.00
CAS No.: 2165689-24-5
Catalog No.: 192853
Purity: 95%
MF: C12H15NO2
MW: 205.257
Storage: 2-8 degree Celsius
SMILES: O1C[C@H](CCC1)NC(C1=CC=CC=C1)=O
Catalog No.: 192853
Purity: 95%
MF: C12H15NO2
MW: 205.257
Storage: 2-8 degree Celsius
SMILES: O1C[C@H](CCC1)NC(C1=CC=CC=C1)=O
(S)-N-(tetrahydro-2H-pyran-3-yl)benzamide; CAS No.: 2165689-24-5; (S)-N-(tetrahydro-2H-pyran-3-yl)benzamide. PROPERTIES: This tetrahydropyran-substituted benzamide has molecular formula C12H15NO2. It appears as a white crystalline powder. The (S)-N-(tetrahydro-2H-pyran-3-yl)benzamide demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 100-105 C, and it has a molecular weight of approximately 209.26 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may undergo hydrolysis upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The (S)-N-(tetrahydro-2H-pyran-3-yl)benzamide serves as a valuable intermediate in the synthesis of kinase inhibitors for cancer therapy where the tetrahydropyran ring provides essential hydrogen bonding interactions with kinase residues (as detailed in medicinal chemistry literature). The benzamide group forms ionic interactions with catalytic residues. Additionally, the compound functions as a building block in the preparation of bioconjugates for drug delivery systems where the amide group reacts with targeting moieties, as described in pharmaceutical sciences journals. The amide group can be further functionalized through hydrolysis or amidation reactions to produce various derivatives for chemical research applications.
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