9-methyl-9H-purine-6-carboxylic acid
$400.00
CAS No.: 1095822-37-9
Catalog No.: 192846
Purity: 95%
MF: C7H6N4O2
MW: 178.151
Storage: 2-8 degree Celsius
SMILES: CN1C2=NC=NC(=C2N=C1)C(=O)O
Catalog No.: 192846
Purity: 95%
MF: C7H6N4O2
MW: 178.151
Storage: 2-8 degree Celsius
SMILES: CN1C2=NC=NC(=C2N=C1)C(=O)O
9-methyl-9H-purine-6-carboxylic acid; CAS No.: 1095822-37-9; 9-methyl-9H-purine-6-carboxylic acid. PROPERTIES: This methylated purine carboxylic acid has molecular formula C6H5N4O2. It appears as a white crystalline powder. The 9-methyl-9H-purine-6-carboxylic acid demonstrates limited water solubility but good solubility in polar aprotic solvents like DMSO and DMF. Its melting point ranges between 200-205 C, and it has a molecular weight of approximately 167.13 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong bases and may decarboxylate upon exposure to high temperatures above 200 C. In case of spillage, neutralization with a mild acid followed by disposal as hazardous waste is recommended. APPLICATIONS: The 9-methyl-9H-purine-6-carboxylic acid functions as a key intermediate in the synthesis of adenosine receptor antagonists for cardiovascular indications where the purine ring provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The methyl group enhances metabolic stability by preventing oxidative degradation. Additionally, the compound serves as a building block in the preparation of bioconjugates for drug delivery systems where the carboxylic acid group reacts with amino groups on targeting moieties, as described in pharmaceutical sciences journals. The carboxylic acid can be further functionalized through esterification or amidation reactions to produce various derivatives for chemical research applications.
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