6-chloro-9-methyl-9H-purine
$365.00
CAS No.: 2346-74-9
Catalog No.: 192847
Purity: 95%
MF: C6H5ClN4
MW: 168.587
Storage: 2-8 degree Celsius
SMILES: ClC1=C2N=CN(C2=NC=N1)C
Catalog No.: 192847
Purity: 95%
MF: C6H5ClN4
MW: 168.587
Storage: 2-8 degree Celsius
SMILES: ClC1=C2N=CN(C2=NC=N1)C
6-chloro-9-methyl-9H-purine; CAS No.: 2346-74-9; 6-chloro-9-methyl-9H-purine. PROPERTIES: This chloro- and methyl-substituted purine has molecular formula C6H5N4Cl. It appears as a white crystalline powder. The 6-chloro-9-methyl-9H-purine demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 140-145 C, and it has a molecular weight of approximately 162.14 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong bases and may decompose upon exposure to high temperatures above 180 C. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 6-chloro-9-methyl-9H-purine serves as a valuable intermediate in the synthesis of kinase inhibitors for cancer therapy where the purine ring provides essential hydrogen bonding interactions with kinase residues (as reported in medicinal chemistry literature). The chlorine atom forms additional interactions with the kinase active site. Additionally, the compound functions as a building block in the preparation of agrochemicals with fungicidal activity, though this application is mentioned only for informational purposes per your request. The chloro group can be further functionalized through nucleophilic substitution reactions to produce various derivatives for chemical research applications.
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