6-methyl-7H-purine
$300.00
CAS No.: 2004-03-7
Catalog No.: 196325
Purity: 95%
MF: C6H6N4
MW: 134.142
Storage: 2-8 degree Celsius
SMILES: CC1=C2NC=NC2=NC=N1
Catalog No.: 196325
Purity: 95%
MF: C6H6N4
MW: 134.142
Storage: 2-8 degree Celsius
SMILES: CC1=C2NC=NC2=NC=N1
6-methyl-7H-purine; CAS No.: 2004-03-7; 6-methyl-7H-purine. PROPERTIES: This compound presents a 6-methyl-7H-purine structure, combining a methyl group and a purine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 130.0 g/mol (C5H4N4). The melting point ranges between 140-145 C, and it exhibits moderate solubility in common organic solvents like DMSO and DMF while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 6-Methyl-7H-purine serves as a specialized intermediate in pharmaceutical research. Its 6-methyl-7H-purine structure enables diverse reactivity patterns, including nucleophilic substitution at the purine ring and hydrogen bonding interactions through the methyl group. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and nucleic acid-binding proteins. The methyl group provides steric and electronic effects that influence binding interactions with biological targets. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies utilize it as a model system in Medicinal Chemistry journals, focusing on optimizing the 6-methyl-7H-purine scaffold for improved biological activity and pharmacokinetic properties.
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