2,6-dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
$200.00
CAS No.: 20419-68-5
Catalog No.: 196903
Purity: 95%
MF: C10H10Cl2N4O
MW: 273.123
Storage: 2-8 degree Celsius
SMILES: ClC1=NC(=C2N=CN(C2=N1)C1OCCCC1)Cl
Catalog No.: 196903
Purity: 95%
MF: C10H10Cl2N4O
MW: 273.123
Storage: 2-8 degree Celsius
SMILES: ClC1=NC(=C2N=CN(C2=N1)C1OCCCC1)Cl
2,6-dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine; CAS No.: 20419-68-5; 2,6-dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine. PROPERTIES: This dichloro-substituted purine derivative features molecular formula C??H??Cl?N?O with molecular weight 285.15 g/mol. It typically exists as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 130-135 C. Exhibits IR absorption for C-Cl groups (~600-500 cm??) and aromatic C-H stretches. Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a dichloro-substituted purine derivative, 2,6-dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine is predominantly utilized in the synthesis of antiviral agents. It serves as a key intermediate in constructing nucleoside analogs, where the dichloro substituents provide enhanced binding affinity for viral polymerases as demonstrated in medicinal chemistry research (Antiviral Research). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its purine framework enables conjugation to fluorophores with enhanced photostability (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the tetrahydropyran group contributes to improved flame retardancy and mechanical properties (Polymer International).
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