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(Z)-ethyl 2-(piperidin-3-ylidene)acetate hydrochloride
$200.00
CAS No.: 957472-02-5
Catalog No.: 192843
Purity: 95%
MF: C9H16ClNO2
MW: 205.685
Storage: 2-8 degree Celsius
SMILES: Cl.N1C\C(\CCC1)=C/C(=O)OCC
Catalog No.: 192843
Purity: 95%
MF: C9H16ClNO2
MW: 205.685
Storage: 2-8 degree Celsius
SMILES: Cl.N1C\C(\CCC1)=C/C(=O)OCC
(Z)-ethyl 2-(piperidin-3-ylidene)acetate hydrochloride; CAS No.: 957472-02-5; (Z)-ethyl 2-(piperidin-3-ylidene)acetate hydrochloride. PROPERTIES: This piperidylidene-substituted acetate ester salt has molecular formula C10H15N2O2 {HCl. It appears as a white crystalline powder. The (Z)-ethyl 2-(piperidin-3-ylidene)acetate hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 180-185 C (with decomposition), and it has a molecular weight of approximately 229.75 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The (Z)-ethyl 2-(piperidin-3-ylidene)acetate hydrochloride serves as a key intermediate in the synthesis of serotonin receptor antagonists for psychiatric disorders where the piperidine ring provides essential hydrogen bonding interactions with receptor subtypes (as reported in medicinal chemistry literature). The ylidene group enhances metabolic stability by preventing oxidative degradation. Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The ester group can be further functionalized through hydrolysis or amidation reactions to produce various derivatives for chemical research applications.
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