(S)-ethyl 2-(3-amino-2-oxopiperidin-1-yl)acetate hydrochloride
$250.00
CAS No.: 937057-79-9
Catalog No.: 192842
Purity: 95%
MF: C9H17ClN2O3
MW: 236.699
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@@H]1C(N(CCC1)CC(=O)OCC)=O
Catalog No.: 192842
Purity: 95%
MF: C9H17ClN2O3
MW: 236.699
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@@H]1C(N(CCC1)CC(=O)OCC)=O
(S)-ethyl 2-(3-amino-2-oxopiperidin-1-yl)acetate hydrochloride; CAS No.: 937057-79-9; (S)-ethyl 2-(3-amino-2-oxopiperidin-1-yl)acetate hydrochloride. PROPERTIES: This amino- and oxo-substituted piperidine acetate ester salt has molecular formula C10H17N2O3 {HCl. It appears as a white crystalline powder. The (S)-ethyl 2-(3-amino-2-oxopiperidin-1-yl)acetate hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 180-185 C (with decomposition), and it has a molecular weight of approximately 243.73 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The (S)-ethyl 2-(3-amino-2-oxopiperidin-1-yl)acetate hydrochloride serves as a valuable intermediate in the synthesis of dual orexin receptor antagonists for insomnia treatment where the piperidine ring provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The oxo group forms additional hydrogen bonds with receptor residues. Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The ester group can be further functionalized through hydrolysis or amidation reactions to produce various derivatives for chemical research applications.
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