(R)-benzyl 2-methylpiperazine-1-carboxylate
$350.00
CAS No.: 84477-85-0
Catalog No.: 196288
Purity: 95%
MF: C13H18N2O2
MW: 234.299
Storage: 2-8 degree Celsius
SMILES: C[C@H]1N(CCNC1)C(=O)OCC1=CC=CC=C1
Catalog No.: 196288
Purity: 95%
MF: C13H18N2O2
MW: 234.299
Storage: 2-8 degree Celsius
SMILES: C[C@H]1N(CCNC1)C(=O)OCC1=CC=CC=C1
(R)-benzyl 2-methylpiperazine-1-carboxylate; CAS No.: 84477-85-0; (R)-benzyl 2-methylpiperazine-1-carboxylate. PROPERTIES: This compound features a (R)-benzyl 2-methylpiperazine-1-carboxylate structure, combining a benzyl ester, a methyl substituent, and a piperazine ring with defined stereochemistry. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 247.3 g/mol (C13H17N3O). The melting point ranges between 100-105 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: (R)-Benzyl 2-methylpiperazine-1-carboxylate serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its (R)-benzyl 2-methylpiperazine-1-carboxylate structure allows for participation in various reactions, including ester hydrolysis, nucleophilic substitution at the piperazine nitrogen, and chiral resolution. In medicinal chemistry, it is used to develop bioactive molecules targeting G protein-coupled receptors and ion channels. The benzyl ester provides temporary protection for the carboxylic acid, allowing sequential synthesis steps. This compound also functions as a building block in the synthesis of bioactive peptides and depsipeptides. Academic studies employ it as a model compound in Medicinal Chemistry journals, focusing on optimizing the (R)-benzyl 2-methylpiperazine-1-carboxylate scaffold for improved biological activity and target engagement.
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