4-(4-benzylpiperazin-1-yl)aniline
$300.00
CAS No.: 16154-69-1
Catalog No.: 196278
Purity: 95%
MF: C17H21N3
MW: 267.376
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)N1CCN(CC1)C1=CC=C(N)C=C1
Catalog No.: 196278
Purity: 95%
MF: C17H21N3
MW: 267.376
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)N1CCN(CC1)C1=CC=C(N)C=C1
4-(4-benzylpiperazin-1-yl)aniline; CAS No.: 16154-69-1; 4-(4-benzylpiperazin-1-yl)aniline. PROPERTIES: This compound features a 4-(4-benzylpiperazin-1-yl)aniline structure, combining a benzylpiperazine group and an aniline group. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 283.4 g/mol (C18H21N3). The melting point ranges between 100-105 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 4-(4-Benzylpiperazin-1-yl)aniline serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 4-(4-benzylpiperazin-1-yl)aniline structure allows for participation in various reactions, including nucleophilic substitution at the piperazine nitrogen and electrophilic substitution at the aniline ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The benzylpiperazine group provides hydrogen-bonding capabilities for improved target binding. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel benzylpiperazine aniline derivatives based on the 4-(4-benzylpiperazin-1-yl)aniline scaffold.
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