(2S)-2-(2-methoxyphenyl)oxirane
$339.00
CAS No.: 874980-60-6
Catalog No.: 195579
Purity: 95%
MF: C9H10O2
MW: 150.177
Storage: 2-8 degree Celsius
SMILES: COC1=C(C=CC=C1)[C@@H]1OC1
Catalog No.: 195579
Purity: 95%
MF: C9H10O2
MW: 150.177
Storage: 2-8 degree Celsius
SMILES: COC1=C(C=CC=C1)[C@@H]1OC1
(2S)-2-(2-methoxyphenyl)oxirane; CAS No.: 874980-60-6; (2S)-2-(2-methoxyphenyl)oxirane. PROPERTIES: (2S)-2-(2-methoxyphenyl)oxirane is a chiral epoxide with a molecular weight of approximately 162.2 g/mol. This colorless liquid exhibits high reactivity typical of epoxide compounds and demonstrates moderate solubility in non-polar organic solvents. The compound is sensitive to both moisture and temperature fluctuations, necessitating storage in a dry environment at temperatures between -10 C and 0 C. Special handling precautions include the use of inert atmosphere techniques to prevent epoxide ring opening, and all transfers should be performed using dry glassware. The compound presents moderate acute toxicity via inhalation and skin absorption routes. APPLICATIONS: (2S)-2-(2-methoxyphenyl)oxirane functions as a chiral synthone in the preparation of enantiomerically pure compounds. Its epoxide functionality allows for stereospecific ring-opening reactions, making it valuable in the synthesis of chiral pharmaceutical intermediates. In asymmetric synthesis, this compound has been employed in the preparation of -blockers where the chiral center derived from the epoxide influences drug-receptor interactions (source: Tetrahedron: Asymmetry). Additionally, its utility extends to the synthesis of natural product-inspired molecules, where the methoxy-substituted aromatic group contributes to bioactive conformations (source: Natural Product Reports). The compound's ability to undergo catalytic asymmetric transformations further enhances its application in the preparation of enantiomerically enriched drug candidates (source: Angewandte Chemie International Edition).
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