2-(2-bromophenyl)oxazole
$300.00
CAS No.: 92346-48-0
Catalog No.: 196263
Purity: 95%
MF: C9H6BrNO
MW: 224.057
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=CC=C1)C=1OC=CN1
Catalog No.: 196263
Purity: 95%
MF: C9H6BrNO
MW: 224.057
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=CC=C1)C=1OC=CN1
2-(2-bromophenyl)oxazole; CAS No.: 92346-48-0; 2-(2-bromophenyl)oxazole. PROPERTIES: This compound features a 2-(2-bromophenyl)oxazole structure, combining a bromine atom, a phenyl group, and an oxazole ring system. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 236.0 g/mol (C8H5BrN2O). The melting point ranges between 120-125 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 2-(2-Bromophenyl)oxazole serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 2-(2-bromophenyl)oxazole structure allows for participation in various reactions, including palladium-catalyzed cross-coupling reactions at the bromine position and nucleophilic substitution at the oxazole ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The bromine atom provides a handle for introducing aryl, vinyl, or heterocyclic substituents. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel bromophenyl oxazole derivatives based on the 2-(2-bromophenyl)oxazole scaffold.
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