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6-methoxyisoquinolin-4-amine; CAS No.: 1780189-97-0; 6-methoxyisoquinolin-4-amine. PROPERTIES: 6-methoxyisoquinolin-4-amine is a crystalline compound with molecular formula C10H9N3O. It has a melting point between 145-150 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored in a tightly sealed container at room temperature away from acidic vapors. Safety precautions include avoiding ingestion and using standard laboratory PPE due to its potential to cause gastrointestinal upset if swallowed. APPLICATIONS: This methoxy-substituted isoquinoline amine is employed in the development of anticancer agents. The methoxy group at position 6 provides electron-donating effects that enhance binding to tubulin as described in medicinal chemistry studies. In chemical biology, 6-methoxyisoquinolin-4-amine serves as a building block for creating fluorescent biosensors. According to bioanalytical chemistry journals, the isoquinoline scaffold's natural fluorescence allows for detection of specific analytes with limits approaching picomolar concentrations.