4-bromo-8-(trifluoromethyl)isoquinoline
$450.00
CAS No.: 1780593-58-9
Catalog No.: 192296
Purity: 95%
MF: C10H5BrF3N
MW: 276.055
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=CC2=C(C=CC=C12)C(F)(F)F
Catalog No.: 192296
Purity: 95%
MF: C10H5BrF3N
MW: 276.055
Storage: 2-8 degree Celsius
SMILES: BrC1=CN=CC2=C(C=CC=C12)C(F)(F)F
4-bromo-8-(trifluoromethyl)isoquinoline; CAS No.: 1780593-58-9; 4-bromo-8-(trifluoromethyl)isoquinoline. PROPERTIES: 4-bromo-8-(trifluoromethyl)isoquinoline is a crystalline substance with molecular formula C10H5BrF3N2. It has a melting point of approximately 145-150 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated, trifluoromethyl-substituted isoquinoline is used in the development of anticancer prodrugs. The bromine substituent serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 4-bromo-8-(trifluoromethyl)isoquinoline serves as a building block for creating photoaffinity labels. According to biochemical journals, the isoquinoline scaffold provides a fluorescent signal while the bromine group enables photoinduced cross-linking with target proteins.
Reviews
Write Your Own Review