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6-bromoisoquinolin-5-amine; CAS No.: 850198-02-6; 6-bromoisoquinolin-5-amine. PROPERTIES: 6-bromoisoquinolin-5-amine is a crystalline compound with molecular formula C9H6BrN3. It has a melting point between 155-160 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored in a tightly sealed container at room temperature away from acidic vapors. Safety precautions include avoiding ingestion and using standard laboratory PPE due to its potential to cause gastrointestinal upset if swallowed. APPLICATIONS: This brominated isoquinoline amine is employed in the development of anticancer agents. The bromine substituent provides a site for palladium-catalyzed cross-coupling reactions as detailed in organic chemistry textbooks. According to cancer research publications, derivatives of 6-bromoisoquinolin-5-amine have demonstrated topo-isomerase II inhibition properties. Additionally, the compound serves as a fluorescent marker in nucleic acid studies due to the isoquinoline scaffold's natural fluorescence.