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4-methoxyisoquinoline-6-carboxylic acid; CAS No.: 2512190-91-7; 4-methoxyisoquinoline-6-carboxylic acid. PROPERTIES: 4-methoxyisoquinoline-6-carboxylic acid appears as a white powder with molecular weight 203.2 g/mol. It has a melting point between 210-215 C and shows limited aqueous solubility but good solubility in DMSO. Proper storage involves maintaining in a sealed container at room temperature away from acidic vapors. Safety precautions include wearing protective gloves and eye protection as this compound may cause skin and eye irritation. APPLICATIONS: This methoxy-substituted isoquinoline carboxylic acid is employed in the development of antimalarial agents. The methoxy group provides a site for PEGylation, enhancing the pharmacokinetic properties of the molecule as reported in tropical medicine research. In materials science, 4-methoxyisoquinoline-6-carboxylic acid derivatives have found use in creating self-assembled monolayers for surface modification. According to materials chemistry journals, the isoquinoline core promotes adsorption onto metal surfaces while the carboxylic acid group imparts chemical functionality.