5,6,7,8-tetrahydroisoquinolin-5-amine hydrochloride
$343.00
CAS No.: 1246552-20-4
Catalog No.: 192728
Purity: 95%
MF: C9H13ClN2
MW: 184.67
Storage: 2-8 degree Celsius
SMILES: Cl.C1=NC=CC=2C(CCCC12)N
Catalog No.: 192728
Purity: 95%
MF: C9H13ClN2
MW: 184.67
Storage: 2-8 degree Celsius
SMILES: Cl.C1=NC=CC=2C(CCCC12)N
5,6,7,8-tetrahydroisoquinolin-5-amine hydrochloride; CAS No.: 1246552-20-4; 5,6,7,8-tetrahydroisoquinolin-5-amine hydrochloride. PROPERTIES: This tetrahydroisoquinoline amine salt has molecular formula C9H13N2 {HCl. It generally appears as a white crystalline powder. The 5,6,7,8-tetrahydroisoquinolin-5-amine hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 200-205 C (with decomposition), and it has a molecular weight of approximately 179.67 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 5,6,7,8-tetrahydroisoquinolin-5-amine hydrochloride functions as a critical intermediate in the synthesis of dual orexin receptor antagonists for insomnia treatment where the amine group provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). Additionally, the compound serves as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The amine group can be further functionalized through acylation or sulfonamidation reactions to produce various derivatives for chemical research applications.
Reviews
Write Your Own Review