(3S)-N-tert-butyldecahydroisoquinoline-3-carboxamide
$350.00
CAS No.: 136465-81-1
Catalog No.: 196241
Purity: 95%
MF: C14H26N2O
MW: 238.375
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)NC(=O)[C@H]1NCC2CCCCC2C1
Catalog No.: 196241
Purity: 95%
MF: C14H26N2O
MW: 238.375
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)NC(=O)[C@H]1NCC2CCCCC2C1
(3S)-N-tert-butyldecahydroisoquinoline-3-carboxamide; CAS No.: 136465-81-1; (3S)-N-tert-butyldecahydroisoquinoline-3-carboxamide. PROPERTIES: This compound presents a (3S)-N-tert-butyldecahydroisoquinoline-3-carboxamide structure, featuring a chiral center, a tert-butyl amide group, and a fully hydrogenated isoquinoline framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 227.3 g/mol (C14H25NO). The melting point ranges between 100-105 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: (3S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide serves as a specialized intermediate in pharmaceutical research. Its (3S)-N-tert-butyldecahydroisoquinoline-3-carboxamide structure enables diverse reactivity patterns, including amide bond formation and chiral resolution. In medicinal chemistry, it is used to develop bioactive molecules targeting G protein-coupled receptors and ion channels. The tert-butyl amide group provides steric protection and metabolic stability. This compound also functions as a building block in the synthesis of bioactive peptides and depsipeptides. Academic studies utilize it as a model system in Medicinal Chemistry journals, focusing on optimizing the (3S)-N-tert-butyldecahydroisoquinoline-3-carboxamide scaffold for improved biological activity and target engagement.
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