2-phenylisoindoline-1,3-dione
$200.00
CAS No.: 520-03-6
Catalog No.: 196240
Purity: 95%
MF: C14H9NO2
MW: 223.231
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)N1C(C2=CC=CC=C2C1=O)=O
Catalog No.: 196240
Purity: 95%
MF: C14H9NO2
MW: 223.231
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)N1C(C2=CC=CC=C2C1=O)=O
2-phenylisoindoline-1,3-dione; CAS No.: 520-03-6; 2-phenylisoindoline-1,3-dione. PROPERTIES: This compound features a 2-phenylisoindoline-1,3-dione structure, combining a phenyl substituent and an isoindoline-1,3-dione framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 229.2 g/mol (C14H9NO2). The melting point ranges between 200-205 C, and it exhibits moderate solubility in common organic solvents like DMSO and DMF while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 2-Phenylisoindoline-1,3-dione serves as a valuable intermediate in pharmaceutical and chemical synthesis. Its 2-phenylisoindoline-1,3-dione structure enables participation in various reactions, including nucleophilic substitution at the isoindoline ring and electrophilic substitution at the phenyl group. In medicinal chemistry, it is used to develop bioactive molecules targeting the central nervous system and inflammatory pathways. The phenyl substituent provides additional conjugation that enhances binding to biological targets. This compound also functions as a building block in the synthesis of complex carbohydrates and glycosides. Academic studies employ it as a model compound in Medicinal Chemistry journals, focusing on optimizing the 2-phenylisoindoline-1,3-dione scaffold for improved biological activity and pharmacokinetic properties.
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