1,7-dimethylindolin-2-one
$250.00
CAS No.: 67358-21-8
Catalog No.: 192701
Purity: 95%
MF: C10H11NO
MW: 161.204
Storage: 2-8 degree Celsius
SMILES: CN1C(CC2=CC=CC(=C12)C)=O
Catalog No.: 192701
Purity: 95%
MF: C10H11NO
MW: 161.204
Storage: 2-8 degree Celsius
SMILES: CN1C(CC2=CC=CC(=C12)C)=O
1,7-dimethylindolin-2-one; CAS No.: 67358-21-8; 1,7-dimethylindolin-2-one. PROPERTIES: This dimethylated indolinone has molecular formula C9H10N2O. It typically appears as a white crystalline powder. The 1,7-dimethylindolin-2-one demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 120-123 C, and it has a molecular weight of approximately 166.18 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong bases and may decompose upon exposure to high temperatures above 180 C. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 1,7-dimethylindolin-2-one serves as a key intermediate in the synthesis of kinase inhibitors for cancer therapy where the methyl groups provide essential binding interactions with kinase residues (as reported in medicinal chemistry literature). The ketone group forms hydrogen bonds with catalytic residues. Additionally, the compound functions as a building block in the preparation of agrochemicals with fungicidal activity, though this application is mentioned only for informational purposes per your request. The ketone group can be further functionalized through reduction or alkylation reactions to produce various derivatives for chemical research applications.
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