methyl 5-(benzyloxy)-2-methyl-1H-indole-3-carboxylate
$490.00
CAS No.: 1671064-19-9
Catalog No.: 192673
Purity: 95%
MF: C18H17NO3
MW: 295.338
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC=1C=C2C(=C(NC2=CC1)C)C(=O)OC
Catalog No.: 192673
Purity: 95%
MF: C18H17NO3
MW: 295.338
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC=1C=C2C(=C(NC2=CC1)C)C(=O)OC
methyl 5-(benzyloxy)-2-methyl-1H-indole-3-carboxylate; CAS No.: 1671064-19-9; methyl 5-(benzyloxy)-2-methyl-1H-indole-3-carboxylate. PROPERTIES: This benzyloxy-substituted indole ester has molecular formula C16H15NO3. It generally appears as a pale yellow crystalline solid. The methyl 5-(benzyloxy)-2-methyl-1H-indole-3-carboxylate demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate but limited water solubility. Its melting point ranges between 98-102 C, and it has a molecular weight of approximately 269.29 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may hydrolyze to the corresponding carboxylic acid upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The methyl 5-(benzyloxy)-2-methyl-1H-indole-3-carboxylate serves as a valuable intermediate in the synthesis of cannabinoid receptor antagonists for metabolic disorders where the benzyloxy group provides essential lipophilicity for receptor interaction (as detailed in medicinal chemistry literature). The ester group allows for further functionalization through hydrolysis or transesterification reactions. Additionally, the compound functions as a building block in the preparation of liquid crystal materials with specific dielectric properties, useful in display technologies with response times below 20 milliseconds as described in materials chemistry journals. The benzyloxy group can be further functionalized through hydrogenolysis or alkylation reactions to produce various derivatives for chemical research applications.
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