2,3,6-trimethyl-1H-indol-5-amine; CAS No.: 165614-76-6; 2,3,6-trimethyl-1H-indol-5-amine. PROPERTIES: This polycyclic amine has molecular formula C9H10N2. It typically appears as a colorless to pale yellow oil. The 2,3,6-trimethyl-1H-indol-5-amine demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate but limited water solubility. Its boiling point ranges between 185-190 C at 760 mmHg, and it has a molecular weight of approximately 146.19 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong oxidizing agents and may form explosive peroxides upon prolonged exposure to air. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 2,3,6-trimethyl-1H-indol-5-amine functions as a key intermediate in the synthesis of melatonin receptor agonists for sleep disorders where the methyl groups provide essential lipophilicity for receptor binding (as reported in medicinal chemistry literature). Additionally, the compound serves as a building block in the preparation of agrochemicals with fungicidal activity, though this application is mentioned only for informational purposes per your request. The amine group can be further functionalized through acylation or alkylation reactions to produce various derivatives for chemical research applications.