(S)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate
$400.00
CAS No.: 955406-13-0
Catalog No.: 192666
Purity: 95%
MF: C12H19N3O2
MW: 237.303
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C[C@H](CCC12)NC(OC(C)(C)C)=O
Catalog No.: 192666
Purity: 95%
MF: C12H19N3O2
MW: 237.303
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C[C@H](CCC12)NC(OC(C)(C)C)=O
(S)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate; CAS No.: 955406-13-0; (S)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate. PROPERTIES: This chiral carbamate-protected tetrahydroindazole has molecular formula C12H19N3O2. It generally appears as a white crystalline powder. The (S)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate exhibits limited water solubility but good solubility in polar aprotic solvents like DMSO and DMF. Its melting point is approximately 108-112 C, and it has a molecular weight of about 237.3 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may undergo carbamate hydrolysis upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The (S)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate serves as a critical intermediate in the synthesis of chiral agrochemicals with herbicidal activity where the tetrahydroindazole ring provides essential binding interactions with plant enzymes (as detailed in agrochemical chemistry literature, though this application is mentioned only for informational purposes per your request). The chiral center ensures proper orientation for optimal activity. Additionally, the compound functions as a building block in the preparation of chiral ligands for asymmetric catalysis, achieving enantiomeric excesses above 95% in certain hydrogenation reactions as reported in synthetic chemistry journals. The carbamate protecting group allows for controlled deprotection under mild acidic conditions.
Reviews
Write Your Own Review