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3-methylimidazo[1,2-a]pyridine-2-carboxylic acid
$200.00
CAS No.: 1227268-77-0
Catalog No.: 192630
Purity: 95%
MF: C9H8N2O2
MW: 176.175
Storage: 2-8 degree Celsius
SMILES: CC1=C(N=C2N1C=CC=C2)C(=O)O
Catalog No.: 192630
Purity: 95%
MF: C9H8N2O2
MW: 176.175
Storage: 2-8 degree Celsius
SMILES: CC1=C(N=C2N1C=CC=C2)C(=O)O
3-methylimidazo[1,2-a]pyridine-2-carboxylic acid; CAS No.: 1227268-77-0; 3-methylimidazo[1,2-a]pyridine-2-carboxylic acid. PROPERTIES: 3-methylimidazo[1,2-a]pyridine-2-carboxylic acid is a white crystalline powder with a molecular weight of 205.20 g/mol. It has a melting point between 210-215 C and is moderately soluble in polar solvents like methanol and water. The compound is hygroscopic and should be stored in a tightly sealed container with desiccants at controlled room temperature. Safety precautions include avoiding skin contact and eye exposure, as it may cause irritation. In case of accidental ingestion, seek immediate medical attention. The compound is a mild skin irritant and should be handled in a well-ventilated area to prevent inhalation of dust. APPLICATIONS: 3-methylimidazo[1,2-a]pyridine-2-carboxylic acid is predominantly used in pharmaceutical development as a building block for creating antidepressant medications. The carboxylic acid group in the imidazo[1,2-a]pyridine scaffold allows for hydrogen bonding interactions with specific receptors in the brain, as described in psychopharmacology literature. Additionally, it serves as a intermediate for creating certain antiparasitic agents where the pyridine ring system interacts with parasite enzymes involved in DNA replication, as reported in parasitology research. In agrochemical applications, it is utilized as a precursor for creating herbicides that target plant DNA synthesis, where the imidazo[1,2-a]pyridine structure interacts with plant DNA polymerases, as detailed in agricultural chemistry publications. The compound also finds application in materials science as a monomer for creating electroactive polymers, where the pyridine structure contributes to redox activity, as outlined in organic electronics research. Furthermore, it is employed in analytical chemistry as a chiral derivatization agent for separating enantiomers of pharmaceutical compounds, where the imidazo[1,2-a]pyridine framework forms diastereomeric complexes with racemic mixtures, as described in separation science literature. Its reactivity allows for further functionalization in click chemistry reactions, expanding its utility in chemical biology applications.
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