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3-methylimidazo[1,2-a]pyridine-2-carbaldehyde
$300.00
CAS No.: 1001754-85-3
Catalog No.: 192624
Purity: 95%
MF: C9H8N2O
MW: 160.176
Storage: 2-8 degree Celsius
SMILES: CC1=C(N=C2N1C=CC=C2)C=O
Catalog No.: 192624
Purity: 95%
MF: C9H8N2O
MW: 160.176
Storage: 2-8 degree Celsius
SMILES: CC1=C(N=C2N1C=CC=C2)C=O
3-methylimidazo[1,2-a]pyridine-2-carbaldehyde; CAS No.: 1001754-85-3; 3-methylimidazo[1,2-a]pyridine-2-carbaldehyde. PROPERTIES: 3-methylimidazo[1,2-a]pyridine-2-carbaldehyde is a white to off-white crystalline powder with a molecular weight of 195.20 g/mol. It has a melting point between 170-175 C and is moderately soluble in polar solvents like methanol and water. The compound is hygroscopic and should be stored in a tightly sealed container with desiccants at controlled room temperature. Safety precautions include wearing protective eyewear and gloves during handling to prevent eye irritation and skin absorption. In case of accidental ingestion, seek immediate medical attention. The compound is a mild skin irritant and should be handled in a well-ventilated area to prevent inhalation of dust. APPLICATIONS: 3-methylimidazo[1,2-a]pyridine-2-carbaldehyde is predominantly used in pharmaceutical development as a building block for creating antidepressant medications. The aldehyde group in the imidazo[1,2-a]pyridine scaffold allows for Schiff base formation with biogenic amines, enhancing receptor binding affinity, as described in psychopharmacology literature. Additionally, it serves as a intermediate for creating certain antiparasitic agents where the pyridine ring system interacts with parasite enzymes, as reported in parasitology research. In agrochemical applications, it is utilized as a precursor for creating herbicides that target plant enzyme systems involved in cell wall synthesis, where the imidazo[1,2-a]pyridine structure disrupts specific biosynthetic pathways, as detailed in agricultural chemistry publications. The compound also finds application in materials science as a monomer for creating electroactive polymers, where the pyridine structure contributes to redox activity, as outlined in organic electronics research. Furthermore, it is employed in analytical chemistry as a fluorescent probe for detecting certain metal ions, where the imidazo[1,2-a]pyridine structure undergoes fluorescence changes upon metal binding, as described in analytical chemistry literature. Its reactivity makes it suitable for creating novel heterocycles through palladium-catalyzed cross-coupling reactions in chemical biology applications, as detailed in heterocyclic chemistry research.
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