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8-bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine
$300.00
CAS No.: 1298031-94-3
Catalog No.: 197700
Purity: 95%
MF: C7H5BrClN3
MW: 246.495
Storage: 2-8 degree Celsius
SMILES: BrC=1C=2N(N=C(C1)Cl)C=C(N2)C
Catalog No.: 197700
Purity: 95%
MF: C7H5BrClN3
MW: 246.495
Storage: 2-8 degree Celsius
SMILES: BrC=1C=2N(N=C(C1)Cl)C=C(N2)C
8-bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine; CAS No.: 1298031-94-3;8-bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine. PROPERTIES: 8-bromo-6-chloro-2-methylimidazo[1,2-b]pyridazine is a polyhalogenated heterocycle with a molecular weight of 257.01 g/mol. This off-white crystalline solid has a melting point between 135-138 C. The molecule features an imidazo[1,2-b]pyridazine ring system with a bromo substituent at position 8, a chloro group at position 6, and a methyl group at position 2. It demonstrates moderate solubility in common organic solvents such as methanol and acetone but limited water solubility. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the multiple halogen substituents' potential to release toxic fumes when heated and the heterocycle's general toxicity. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily serves as a building block in the synthesis of agrochemicals and pharmaceuticals, where the brominated and chlorinated imidazopyridazine structure provides essential binding affinity to target enzymes. In medicinal chemistry, it has been employed in developing antimicrobial agents targeting bacterial and fungal pathogens and has shown utility in creating herbicides with selective activity against grassy weeds. The imidazopyridazine scaffold has also garnered interest in materials science for developing fluorescent probes, leveraging the electron-deficient imidazole core to tune optical properties. These applications are documented in publications from the Journal of Medicinal Chemistry and the Journal of Fluorescence.
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