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1-(methylsulfonyl)imidazolidin-2-one
$200.00
CAS No.: 41730-79-4
Catalog No.: LT0235
Purity: 95%
MF: C4H8N2O3S
MW: 164.186
Storage: 2-8 degree Celsius
SMILES: CS(=O)(=O)N1C(NCC1)=O
Catalog No.: LT0235
Purity: 95%
MF: C4H8N2O3S
MW: 164.186
Storage: 2-8 degree Celsius
SMILES: CS(=O)(=O)N1C(NCC1)=O
CAS NO.: 41730-79-4;1-(methylsulfonyl)imidazolidin-2-one. PROPERTIES: This methylsulfonyl heterocycle presents as a white crystalline solid with a molecular weight of approximately 175.2 g/mol. The 1-(methylsulfonyl)imidazolidin-2-one combines an imidazolidinone ring with a methyl sulfonyl group. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The 1-(methylsulfonyl)imidazolidin-2-one serves as a key intermediate in the synthesis of various pharmaceuticals. Its imidazolidinone framework provides opportunities for constructing antiviral agents and metalloenzyme inhibitors. Research teams utilize this compound as a starting material for creating neuraminidase inhibitors and matrix metalloproteinase inhibitors. The methylsulfonyl group enhances metabolic resistance in resulting drug candidates. Additionally, it serves as a building block for creating chiral auxiliaries for asymmetric synthesis and fluorescent probes for bioimaging applications.
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