ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate
$225.00
CAS No.: 169616-29-9
Catalog No.: 192620
Purity: 95%
MF: C13H15N3O2
MW: 245.282
Storage: 2-8 degree Celsius
SMILES: NC=1N=CN(C1C(=O)OCC)CC1=CC=CC=C1
Catalog No.: 192620
Purity: 95%
MF: C13H15N3O2
MW: 245.282
Storage: 2-8 degree Celsius
SMILES: NC=1N=CN(C1C(=O)OCC)CC1=CC=CC=C1
ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate; CAS No.: 169616-29-9; ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate. PROPERTIES: ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate is a white to off-white crystalline powder with a molecular weight of 278.30 g/mol. It has a melting point between 180-185 C and is moderately soluble in polar solvents like methanol and water. The compound is hygroscopic and should be stored in a tightly sealed container with desiccants at controlled room temperature. Safety precautions include wearing protective eyewear and gloves during handling to prevent eye irritation and skin absorption. In case of accidental ingestion, seek immediate medical attention. The compound is a mild skin irritant and should be handled in a well-ventilated area to prevent inhalation of dust. APPLICATIONS: ethyl 4-amino-1-benzyl-1H-imidazole-5-carboxylate is predominantly used in pharmaceutical development as a building block for creating antiviral medications. The imidazole ring with the amino and benzyl substituents provides a unique scaffold for interacting with viral proteases, as described in antiviral chemistry literature. Additionally, it serves as a intermediate for creating beta-lactamase inhibitors where the imidazole framework enhances enzyme binding affinity, as reported in antimicrobial research. In agrochemical applications, it is utilized as a precursor for creating fungicides that target fungal translation machinery, where the imidazole ring system interacts with ribosomal proteins, as detailed in pesticide chemistry publications. The compound also finds application in materials science as a chiral dopant for creating organic semiconductors with improved charge carrier mobility, where the imidazole structure induces specific packing arrangements, as outlined in organic electronics studies. Furthermore, it is employed in analytical chemistry as a chiral resolving agent for separating enantiomers of pharmaceutical compounds, where the imidazole framework forms diastereomeric complexes with racemic mixtures, as described in separation science literature. Its reactivity makes it suitable for creating novel amines through alkylation reactions in chemical biology applications, as detailed in medicinal chemistry research.
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