N-(4-oxochroman-6-yl)acetamide
$300.00
CAS No.: 103646-29-3
Catalog No.: 196236
Purity: 95%
MF: C11H11NO3
MW: 205.213
Storage: 2-8 degree Celsius
SMILES: O=C1CCOC2=CC=C(C=C12)NC(C)=O
Catalog No.: 196236
Purity: 95%
MF: C11H11NO3
MW: 205.213
Storage: 2-8 degree Celsius
SMILES: O=C1CCOC2=CC=C(C=C12)NC(C)=O
N-(4-oxochroman-6-yl)acetamide; CAS No.: 103646-29-3; N-(4-oxochroman-6-yl)acetamide. PROPERTIES: This compound presents an N-(4-oxochroman-6-yl)acetamide structure, combining an acetamide group and a chroman-4-one framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 221.2 g/mol (C11H11NO3). The melting point ranges between 130-135 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: N-(4-Oxochroman-6-yl)acetamide serves as a specialized intermediate in pharmaceutical research. Its N-(4-oxochroman-6-yl)acetamide structure enables diverse reactivity patterns, including nucleophilic substitution at the acetamide group and electrophilic substitution at the chroman-4-one ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The acetamide group provides hydrogen-bonding capabilities for improved target binding. This compound also functions as a building block in the synthesis of fluorescent probes and bioconjugation reagents. Academic studies utilize it as a model system in Medicinal Chemistry journals, focusing on optimizing the N-(4-oxochroman-6-yl)acetamide scaffold for improved biological activity and pharmacokinetic properties.
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