methyl 8-bromo-2H-chromene-5-carboxylate
$450.00
CAS No.: 2417387-84-7
Catalog No.: 192714
Purity: 95%
MF: C11H9BrO3
MW: 269.094
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=2C=CCOC12)C(=O)OC
Catalog No.: 192714
Purity: 95%
MF: C11H9BrO3
MW: 269.094
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C(C=2C=CCOC12)C(=O)OC
methyl 8-bromo-2H-chromene-5-carboxylate; CAS No.: 2417387-84-7; methyl 8-bromo-2H-chromene-5-carboxylate. PROPERTIES: This brominated chromene ester has molecular formula C10H7BrO3. It typically appears as a pale yellow crystalline powder. The methyl 8-bromo-2H-chromene-5-carboxylate demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 100-105 C, and it has a molecular weight of approximately 251.07 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong bases and may undergo hydrolysis upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The methyl 8-bromo-2H-chromene-5-carboxylate functions as a key intermediate in the synthesis of cannabinoid receptor antagonists for metabolic disorders where the bromine atom provides essential binding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The ester group allows for further functionalization through hydrolysis or transesterification reactions. Additionally, the compound serves as a building block in the preparation of liquid crystal materials with specific dielectric properties, useful in display technologies with response times below 20 milliseconds as described in materials chemistry journals. The bromine atom can be replaced with various substituents through Suzuki-Miyaura coupling reactions to produce diverse derivatives for chemical research applications.
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